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In this lecture ´´Adrenocortical Hormones´´ are explained. Section one is about ´´Corticosteroids´´. In the beginning, educator talks about adrenal glands. Then moves to corticosteroids. Following this, synthesis and secretion of corticosteroids is discussed. After that synthetic pathways for adrenal steroids is elucidated. Furthermore, adrenal steroid hormones in adults are highlighted. Then information about adrenocortical hormones transport is given. At last, adrenocortical hormone metabolism is elaborated.
Section two is about ‘’Aldosterone’’. Initially, educator reports functions of mineralocorticoid – aldosterone. After that, renal and circulatory effects of aldosterone are highlighted. This is followed by functions of aldosterone. Then cellular mechanism of aldosterone action is exhibited. Subsequently, regulation of aldosterone secretion is discussed.
Section three is about ‘’Glucocorticoids’’. At first, educator talks about functions of glucocorticoids. Then effects of cortisol on carbohydrate metabolism are reported. This is followed by elucidation of effects of cortisol on protein metabolism. Likewise, effects of cortisol on fat metabolism is discussed. Furthermore, information is delivered about cortisol in resisting stress and inflammation. Afterwards, anti-inflammatory effects of cortisol are pursued. Educator's next theme of discussion is prevention of development of inflammation. Later on, resolution of inflammation is explained. At last, other effects of cortisol are elaborated by the educator.
Regulation of Cortisol and Androgens
Section four is about ‘’Regulation of Cortisol and Androgens’’. Educator begins by discussing regulation of cortisol secretion. Then inhibitory effect of cortisol is highlighted. Following this, circadian rhythm of glucocorticoid secretion is graphically illustrated. Afterwards, educator sheds light on synthesis and secretion of ACTH. In the end, information about adrenal androgens is given.
Abnormalities of Adrenocortical Secretion
Section five is about ‘’Abnormalities of Adrenocortical Secretion’’. Educator's first theme of elucidation is hypoadrenalism - Addison’s disease. After that hyperadrenalism - Cushing’s syndrome is discussed. Then Primary aldosteronism - Conn’s syndrome is elaborated. Lastly, educator talks about adrenogenital syndrome.