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Lecture´s Description

This short video clip is the brief explanation of Amphetamine.

Amphetamine is a CNS stimulant drug used in treatment of attention deficit hyperactive disorder. Inside the brain, the amphetamine binds to the transporter proteins for monoamines like dopamine and taken up into neurons. It binds with the vesicular monoamine transporter 2 and prevent the storage of dopamine into storage vesicle. It disrupts the storage vesicle and release more dopamine.

Amphetamine also cause the monoamine transporter proteins to run in reverse, leading to the increased release of monoamines that bind to postsynaptic receptor and stimulate nervous system. Also, it can block the reuptake of dopamine.

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