In this lecture ´´Antibodies´´ are explained. Section one is about ´´Immunoglobulins´´. At first, elucidation of structure is given. Educator tells that each light-chain polypeptide usually consists of about 220 amino acids and each heavy chain consists of about 440 amino acids. Then information is conveyed about light and heavy chain. Lastly, functions are reported.
Section two is about ‘’Kinetics’’. Earlier in this section, immunoglobulin classes are pursued. These include immunoglobulin –Ƴ, immunoglobulin µ, immunoglobulin a, immunoglobulin δ, and immunoglobulin e. Educator explain all of them in succession. After that primary antibody response is elaborated. This is followed by secondary antibody response. In the end, primary vs secondary response is comparatively illustrated.
Section three is about ‘’Diversity’’. Firstly, educator talks about diversity generation. Each human can synthesize antibodies that can bind to more than 1013 (10 trillion) different epitopes. Then combinatorial joining is explained. At last, light is shed on splice site variation/somatic hyper mutation.
Section four is about ‘’Clonal Selection’’. Educator begins this section with the explanation of selection and tells that specific cells are stimulated by antigens to reproduce and form B-cell clones containing the same genetic information known as clonal selection. Then briefly elucidates the 4 tenets. At last, antigen-dependent and independent period is discussed in detail.
Section five is about ‘’Action’’. In the beginning, educator exhibits the action of antibodies. After that discusses neutralization. Next focus is the elucidation of opsonization. Opsonization is the process by which microorganisms or other foreign particles are coated with antibody or complement and thus prepared for "recognition" and ingestion by phagocytic cells. In the end, immune complex formation is pursued.