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91xff61rrvixa8hvneml 180829 s0 wasay abdul antibodies intro
03:03
Antibodies
9aqz5gqriyljykl5txns 180829 s1 wasay abdul immunoglobulins
05:43
Immunoglobulins
Hrdfnmp2raq82mpgnzax 180829 s2 wasay abdul kinetics
10:47
Kinetics
Cyfbe58qb4bo28wtezao 180829 s3 wasay abdul diversity
06:31
Diversity
Ibmjqxdqrm9l9zwfuuzh 180829 s4 wasay abdul clonal selection
11:14
Clonal Selection
Ksjszsnqrsm3un571jmj 180829 s5 wasay abdul action
10:12
Action

Lecture´s Description

Immunoglobulins
In this lecture ´´Antibodies´´ are explained. Section one is about ´´Immunoglobulins´´. At first, elucidation of structure is given. Educator tells that each light-chain polypeptide usually consists of about 220 amino acids and each heavy chain consists of about 440 amino acids. Then information is conveyed about light and heavy chain. Lastly, functions are reported.


Kinetics
Section two is about ‘’Kinetics’’. Earlier in this section, immunoglobulin classes are pursued. These include immunoglobulin –Ƴ, immunoglobulin µ, immunoglobulin a, immunoglobulin δ, and immunoglobulin e. Educator explain all of them in succession. After that primary antibody response is elaborated. This is followed by secondary antibody response. In the end, primary vs secondary response is comparatively illustrated.


Diversity
Section three is about ‘’Diversity’’. Firstly, educator talks about diversity generation. Each human can synthesize antibodies that can bind to more than 1013 (10 trillion) different epitopes. Then combinatorial joining is explained.  At last, light is shed on splice site variation/somatic hyper mutation.


Clonal Selection
Section four is about ‘’Clonal Selection’’. Educator begins this section with the explanation of selection and tells that specific cells are stimulated by antigens to reproduce and form B-cell clones containing the same genetic information known as clonal selection. Then briefly elucidates the 4 tenets. At last, antigen-dependent and independent period is discussed in detail.


Action
Section five is about ‘’Action’’. In the beginning, educator exhibits the action of antibodies. After that discusses neutralization. Next focus is the elucidation of opsonization. Opsonization is the process by which microorganisms or other foreign particles are coated with antibody or complement and thus prepared for "recognition" and ingestion by phagocytic cells. In the end, immune complex formation is pursued.

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