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Iwf2zk81qk2okvbc8od9 180906 s0 khurshid aqsa cell death intro
Cell Death
Lxosektra2ekeogh23cv 180906 s1 khurshid aqsa apoptosis
Klzemd9wsfoqli1rli94 180906 s2 khurshid aqsa extrinsic apoptotic pathway
Extrinsic Apoptotic Pathway
Y2impvtdryg29h0nbmeo 180906 s3 khurshid aqsa intrinsic apoptotic pathways
Intrinsic Apoptotic Pathways
Hdaih61pqlqvcbu05pps 180906 s4 khurshid aqsa apoptosis regulation
Apoptosis Regulation
Xizzilmvrlsu519i0fhc 180906 s5 khurshid aqsa phagocytosis

Lecture´s Description


In this lecture ´´Cell Death´´ are explained. Section one is about ´´Apoptosis´´. Initially, educator gives definition and explains the process of apoptosis. After that significance of apoptosis is discussed. Educator tells that cells also die when they become damaged or infected. Then necrosis is pursued.

Extrinsic Apoptotic Pathway

Section two is about ''Extrinsic Apoptotic Pathway''. Educator begins by comprehensively explaining caspase mediated pathway. Caspases are intracellular proteases which cleave their target proteins at specific aspartic acids. Then receptor mediated extrinsic pathway is elaborated. The receptors are homotrimers and belong to the tumor necrosis factor (TNF) receptor family.

Intrinsic Apoptotic Pathways

Section three is about ''Intrinsic Apoptotic Pathways''. At first, intrinsic pathway is exhibited. Alongside, fluorescence micrographs of human cancer cells in culture are also presented. After that information about regulatory proteins controlling intrinsic pathways is delivered. Educator tells that Bcl2 proteins regulate the intrinsic pathway of apoptosis.

Apoptosis Regulation

Section four is about ''Apoptosis Regulation''. Prime emphasis is on elucidation of inhibitors of apoptosis. Educator tells that inhibitors of apoptosis (IAPS) proteins were first identified in certain insect viruses (baculoviruses).


Section five is about ''Phagocytosis''. Firstly, introduction is given. Then role of phagocytes is pursued. Likewise, information about apoptosis & disease is given. Furthermore, educator illustrates the process of necrosis during ischemia/reperfusion.

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