Cell Locomotion and Intermediate Filaments

by Khurshid, Aqsa

Cell Biology

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Nxsx2pverzshyl6xtidg 180705 s0 khurshid aqsa cell locomotion and intermediate filaments intro
04:01
Cell Locomotion and Intermediate Filaments
Ouuigcj7rnkhxcn3bowr 180705 s1 khurshid aqsa myosin powered cell movements
14:06
Myosin Powered Cell Movements
3brvb8tcqc2wbxehg667 180705 s2 khurshid aqsa cell movements and mediators
08:52
Cell Movements and Mediators
1xegekuqm24t4wz4ceyi 180705 s3 khurshid aqsa cell locomotion
12:45
Cell Locomotion
Doojtt5r1ew8feztbj28 180705 s4 khurshid aqsa intermediate filaments
07:34
Intermediate Filaments
Yhxxbu6js5ixlnaaeubm 180705 s5 khurshid aqsa role of intermediate filaments
07:33
Role of Intermediate Filaments

Lecture´s Description

Myosin Powered Cell Movements
In this lecture ´´Cell Locomotion and Intermediate Filaments´´ is explained. Section one is about ´´Myosin Powered Cell Movements´´. Educator started this section by the explanation of contractile bundles in non-muscle and muscle cells. This explanation includes the discussion of junctions, integrin and actin-containing stress fibers, localization of myosin, actin filaments, relaxation and contraction of muscles. Moreover, regulation of skeletal muscle contraction is pursued in next few slides.


Cell Movements and Mediators
Section two is about ‘’Cell Movements and Mediators’’. Earlier in this section educator tells that cell locomotion results from the coordination of motions generated by different parts of a cell. Then direction of movement is reported. Discussion continues on types of movement. After that forces produced by assembly of the actin network are focused. Then Elastic Brownian ratchet model comes under consideration. Then educator reveals some information that was made by studying keratinocyte micrograph.


Cell Locomotion
Section three is about ‘’Cell Locomotion’’. Initially, ameboid movement is discussed in detail. This is followed by the fibroblast movements during wound healing. After that chemotaxis is the subject of discussion.


Intermediate Filaments
Section four is about ‘’Intermediate Filaments’’. In the very first slide comparative discussion continues on intermediate filaments and other cytoskeletal fibers. Next is the intermediate filaments tissue distribution. Additionally, distribution of keratin is also reported. Moreover, distribution of Vimentin, Desmin filaments, Glial fibrillary acidic protein, Peripherin, and Neurofilaments are also focused. After that structure of intermediate filaments is illustrated.


Role of Intermediate Filaments
Section five is about ‘’Role of Intermediate Filaments’’. Educator tells that intermediate filaments are dynamic by the presentation of results derived from the experiment conducted with keratin. Intermediate Filament also act as associated proteins (IFAPs). After that intermediate filament functions are elucidated. Finally, effect of keratin network disruption is highlighted. 

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