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Myosin Powered Cell Movements
In this lecture ´´Cell Locomotion and Intermediate Filaments´´ is explained. Section one is about ´´Myosin Powered Cell Movements´´. Educator started this section by the explanation of contractile bundles in non-muscle and muscle cells. This explanation includes the discussion of junctions, integrin and actin-containing stress fibers, localization of myosin, actin filaments, relaxation and contraction of muscles. Moreover, regulation of skeletal muscle contraction is pursued in next few slides.
Cell Movements and Mediators
Section two is about ‘’Cell Movements and Mediators’’. Earlier in this section educator tells that cell locomotion results from the coordination of motions generated by different parts of a cell. Then direction of movement is reported. Discussion continues on types of movement. After that forces produced by assembly of the actin network are focused. Then Elastic Brownian ratchet model comes under consideration. Then educator reveals some information that was made by studying keratinocyte micrograph.
Section three is about ‘’Cell Locomotion’’. Initially, ameboid movement is discussed in detail. This is followed by the fibroblast movements during wound healing. After that chemotaxis is the subject of discussion.
Section four is about ‘’Intermediate Filaments’’. In the very first slide comparative discussion continues on intermediate filaments and other cytoskeletal fibers. Next is the intermediate filaments tissue distribution. Additionally, distribution of keratin is also reported. Moreover, distribution of Vimentin, Desmin filaments, Glial fibrillary acidic protein, Peripherin, and Neurofilaments are also focused. After that structure of intermediate filaments is illustrated.
Role of Intermediate Filaments
Section five is about ‘’Role of Intermediate Filaments’’. Educator tells that intermediate filaments are dynamic by the presentation of results derived from the experiment conducted with keratin. Intermediate Filament also act as associated proteins (IFAPs). After that intermediate filament functions are elucidated. Finally, effect of keratin network disruption is highlighted.