Composition of Extracellular Matrix

by Afridi, Maham

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Data 2fimages 2fsijiqdgqhycgygpsivkz 181016 s0 afridi maham composition of extracellular matrix intro
04:20
Composition of Extracellular Matrix
Data 2fimages 2f39mleuhftyiu5r4hmrta 181016 s1 afridi maham composition and role
17:36
Composition and Role
Data 2fimages 2fgxlxivgtk6mypyp4ioeq 181016 s2 afridi maham macromolecules
19:52
Macromolecules
Data 2fimages 2fbqresegcs4imrc5whd6y 181016 s3 afridi maham types of gags
14:32
Types of GAGS
Data 2fimages 2fbegzjjihq5caosilnqcf 181016 s4 afridi maham collagens
15:42
Collagens
Data 2fimages 2fipwa3tdusgicmae85gsy 181016 s5 afridi maham interaction with fibroblasts
09:12
Interaction with Fibroblasts

Lecture´s Description

Composition and Role
This lecture thoroughly elaborates on Composition of Extracellular Matrix. In section one, the educator primarily focuses on the Composition and Role of Extracellular Matrix. The topic of Composition of Tissues is addressed in the beginning. Subsequently, the educator speaks about The Matrix. Furthermore, Role of Matrix is highlighted followed by an elucidation of Overview of Matrix.


Macromolecules
Section two is about Macromolecules. In this section, the educator deals with the explanation of ECM Production by Cells. Later, light is shed on Macromolecules of ECM and Variability of ECM. Moving forward, the The Proteoglycan Molecules are highlighted followed by a discussion on The Collagen Fibers. The educator then brings Matrix Glycoprotein under consideration and puts forth a description of Glycosaminoglycan (GaG) Chains. Afterwards, light is shed on Groups of GAGs in addition to GAGs Structure and Function. At the end of this section, Defects in the Production of GAGs are brought to light by the educator.


Types of GAGS
In section three the educator talks about Types of GAGS. First of all, the Simplest Form of GAG: Hyaluronan is elucidated in detail. Furthermore, the Role of Hyaluronan is discussed extensively. Apart from this, the educator focuses on the description of Formation of Proteoglycans and deals with the clarification of the concept of Proteoglycans vs Glycoproteins. For a greater understanding, light is shed on the Examples of Proteoglycans. The educator concludes this section by addressing Plasma Membrane Proteoglycans and Syndecans.


Collagens
Section four focuses on Collagens. At first, the educator puts forth an overview of Collagens. Afterwards, various aspects of Collagens are highlighted such as Primary Features of Collagens and Types of Collagens. Furthermore, light is shed on Fibril-Associated Collagens, “Collagen-Like” Proteins, and Secreted Fibril-Associated Collagens.


Interaction with Fibroblasts
Section five gives information regarding Interaction with Fibroblasts. The prime focus of educator in this section is the elucidation of Organization of Collagen Fibrils. After this, the explanation of how Fibroblasts Interact with Collagen takes place. Subsequently, light is shed on the In Vitro Experiments. At the end of this section, the educator elaborates on how Fibroblasts Organize ECM.

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