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In this lecture ´´Eukaryotic Chromosome´´ are explained. Section one is about ´´Structure´´. In the beginning, educator comprehensively explains the structure of chromosome. Then structure of nucleosomes is discussed. Likewise, structure of condensed chromatin is elaborated. Educator tells that nucleosomes are thought to be packed into an irregular spiral or solenoid arrangement, with approximately six nucleosomes per turn.
Section two is about ‘’Chromatin Condensation’’. Earlier in this section, modification of histone tail is pursued. After that scaffold proteins are exhibited. Educator illustrates the electron micrographs of histone-depleted metaphase chromosomes. At last, other proteins in chromatin are also discussed.
Section three is about ‘’Morphology’’. At first, properties of chromosome are reported. Then techniques to study chromosome are discussed. These techniques include giemsa stain, chromosome painting, multicolor fish, and staining of polytene chromosomes. Lastly, elucidation of heterochromatin is given.
Section four is about ‘’Inheritance’’. Educator starts this section with thorough explanation of replication origin. Then detailed information about centromere is given. Following this, telomeres are elaborated. Yeast artificial chromosome (YAC) are also discussed in this section.
Section five is about ‘’Organelle DNA’’. Educator's first subject of discussion is mitochondrial DNA. Educator also reveals an interesting fact that in mammals and most other multicellular organisms, all the mitochondria in the embryo are derived from those in the egg, not the sperm. Then mutation in mitochondrial DNA is pursued. Moving onward, chloroplast DNA is highlighted.