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In this lecture ´´Hypothalamic and Pituitary Hormones´´ are explained. Section one is about ´´Growth Hormone´´. Initially, educator talks about hypothalamic and pituitary hormones. After that clinical uses of hypothalamic hormones and their analogs are discussed. Then growth hormone (somatotropin) is elucidated. Alongside, its pharmacokinetics is reported. Likewise, mechanism of action is explained. Moving onward, clinical uses of recombinant human growth hormone are elaborated. Next, toxicity is focused along with contraindications. Moreover, mecasermin is discussed. At last, educator reports adverse effect.
Growth Hormone Antagonist
Section two is about ‘’Growth Hormone Antagonist’’. Earlier in this section, somatostatin analogs are explained. After that octreotide is discussed along with pharmacodynamics, clinical uses, and adverse effects. Following this, lanreotide is pursued. In the end, pegvisomant is elaborated.
Section three is about ‘’Gonadotropins’’. At first, educator elucidates gonadotropin and human chronic gonadotropin. Then talks about its pharmacokinetics. This is followed by menotropins. Furthermore, Follicle-Stimulating Hormone is elaborated. Afterwards, luteinizing hormone is explained. Subsequently, information is conveyed about human chronic gonadotropin. Concluding this section, educator sheds light on its pharmacokinetics, pharmacodynamics, and toxicity.
GnRH, Analogues and Antagonists
Section four is about ‘’GnRH, Analogues and Antagonists’’. Educator's prime focus is the elucidation of gonadotropin-releasing hormone and its analogs. After that chemistry is discussed. Then pharmacokinetics is pursued along with toxicity. Moving onward, GnRH receptor antagonists are elaborated. Its pharmacokinetics and toxicity are also discussed. Moreover, prolactin is explained. Later on, dopamine agonists are highlighted. Lastly, educator talks about its toxicity.
Posterior Pituitary Hormones
Section five is about ‘’Posterior Pituitary Hormones’’. Initially, educator introduces posterior pituitary hormones. After that oxytocin is discussed. Then its toxicity is pursued. Following this, oxytocin antagonist is highlighted. Moving onward, vasopressin comes under consideration. Subsequently, vasopressin analogues are elaborated. Alongside its mechanism of action is discussed. Lastly, vasopressin antagonists are explained.