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Immune Disorders

Immune Tolerance
In this lecture ´´Immune Disorders´´ are explained. Section one is about ´´Immune Tolerance´´. Educator begins with explanation of acquired immune tolerance. Then negative selection and central tolerance is pursued. At the end, Peripheral Tolerance and Anergy is discussed. Educator tells that the mechanisms happening all over the body is known as peripheral tolerance and these supplement central tolerance.

Type I and II Hypersensitivity
Section two is about ‘’Type I and II Hypersensitivity’’. In the very first slide information about hypersensitivity is given. Next is the elucidation of hypersensitivity I. Then anaphylaxis is discussed. Likewise, hypersensitivity II comes under consideration. Type II hypersensitivity is generally called a cytolytic or cytotoxic reaction.

Type III and IV Hypersensitivity
Section three is about ‘’Type III and IV Hypersensitivity’’. Initially, educator elaborates blood typing and hypersensitivity. After that hypersensitivity III is discussed. Following this, hypersensitivity IV is highlighted at the end of this section. Additionally, educator reveals that a major factor in the type IV reaction is the time required for T cells to migrate to and accumulate near the antigens.

Autoimmune Diseases
Section four is about ‘’Autoimmune Diseases’’. In the beginning, educator introduces autoimmune diseases. Autoimmune disease results from the activation of self-reactive T and B cells. In the next slide, light is shed on the concept that autoantibodies cause autoimmunity. At last, human autoimmune diseases are focused.

Section five is about ‘’Transplantation’’. Earlier in this section, tissue rejection is pursued. After that potential transplantation reactions are elaborated. Following this, graft versus host disease is discussed. Educator tells that organ transplant recipients also can develop graft-versus host disease. In the end, immunodeficiency is highlighted.

Wasay, Abdul
  • Academics: DPT
  • Specialization: Physical Therapy
  • Current: Rehab House Officer
  • Hospital: Pakistan Railway General
  • Location: Rawalpindi, Pakistan
  • Clinical / Teaching Years: 2 / 1
  • Course: Physiology

Mr. Abdul Wasay joined Pakistan Railway General Hospital in March, 2018 after completing Doctor of Physical Therapy from Riphah International University, Islamabad.

Since 2015 he has been working in Pakistan Railway Hospital and Riphah International Hospital Islamabad as a Trainee under supervised clinical practice. 

32 lectures