Immunosuppressive Therapy

by Afzal, Sidra

Pharmacology

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Data 2fimages 2f5gpuwhsgqwsxodhcilot 181009 s0 afzal sidra immunosuppressive therapy intro
02:55
Immunosuppressive Therapy
Data 2fimages 2fe8yljpfvsk6fhyxlzjg7 181009 s1 afzal sidra glucocorticoids and thalidomide
17:55
Glucocorticoids and Thalidomide
Data 2fimages 2febup1c9ysyy82ig8ig9l 181009 s2 afzal sidra calcineurin inhibitors
10:06
Calcineurin Inhibitors
Data 2fimages 2f80amvvot9wxcauc7cx9k 181009 s3 afzal sidra proliferation signal inhibitors
13:02
Proliferation Signal Inhibitors
Data 2fimages 2fdzq3ue7dsbmq7qpmqise 181009 s4 afzal sidra cytotoxic agents
14:16
Cytotoxic Agents
Data 2fimages 2foxkgsqaqs3ce657rx2xd 181009 s5 afzal sidra other cytotoxic and miscellaneous agents
11:45
Other Cytotoxic and Miscellaneous Agents

Lecture´s Description

Glucocorticoids and Thalidomide
The following lecture addresses the topic of Immunosuppressive Therapy. In section one of this lecture, the educator starts off by demonstrating the underlying process of Immunosuppressive Therapy and highlights Sites of Immunosuppressive Drug Action. Following this, a detailed overview of Glucocorticoids is carried out. Moreover, Pharmacokinetics, Anti-inflammatory and Immunosuppressive Effects, Clinical Use and Therapeutic and Adverse Effects of Glucocorticoids are also brought to light. In addition to this, the educator brings to focus Thalidomide and further elaborates on this drug by discussing its Pharmacokinetics, Clinical Use, and Adverse Effects. At the end of this section, a thorough description Thalidomide Derivatives IMiDs presented.


Calcineurin Inhibitors
Section two is committed to the discussion of Calcineurin Inhibitors. In this section, a detailed demonstration of Calcineurin Inhibitors process is presented after which the educator sheds light on Cyclosporine. Various aspects of Cyclosporine such as its Clinical Use and Adverse Effects are highlighted. Afterwards, the educator moves towards Tacrolimus and discusses its Clinical Use and Adverse Effects.


Proliferation Signal Inhibitors
Section three focuses on Proliferation Signal Inhibitors. At the start of this section, the educator highlights the process of Proliferation Signaling Inhibitors. After this, light is shed on the drug Sirolimus and its newer version Everolimus. The Clinical Use and Adverse Effects of these drugs are elucidated. In addition, the drugs Tofacitinib (Xeljanz) and Mycophenolate Mofetil are peculiarly reported followed by a detailed demonstration of their Pharmacokinetics, Clinical Use and Toxicity.


Cytotoxic Agents
Section four focuses on the explanation of Cytotoxic Agents. The educator brings to light the drug Azathioprine and discusses its Pharmacokinetics, Clinical Use, and Adverse Effects. After this, an overview of the drug Cyclophosphamide is provided followed by a demonstration of its Pharmacokinetics, Clinical Use, and Side Effects. At the end of this section, the educator reports the process of Pyrimidine Synthesis Inhibitors and describes few drugs of this category such as Leflunomide, Teriflunomide and Hydroxychloroquine.


Other Cytotoxic and Miscellaneous Agents
In section five, the educator speaks about Other Cytotoxic and Miscellaneous Agents. Many different drugs of this category are highlighted and elaborated upon in detail. The drugs which are elucidated by educator include Methotrexate, Vincristine, Cytarabine, Pentostatin, Dimethyl fumarate (DMF), Glatiramer acetate (GA), and Fingolimod hydrochloride (FH).

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