Multifactorial Disorders

Genetics

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Data 2fimages 2fbk9pbnogsqmcdoy8gljf 190302 s0 afridi maham multifactorial disorders intro
04:28
Multifactorial Disorders
Data 2fimages 2fgnefktoorokqtxehamxs 190302 s1 afridi maham multifactorial inheritance
33:42
Multifactorial Inheritance
Data 2fimages 2f5erjohbctdilfyzd7va8 190302 s2 afridi maham example of multifactorial disorder
09:35
Example of Multifactorial Disorder
Data 2fimages 2fmsjjqwais1wz8ealbh5g 190302 s3 afridi maham polygenic inheritance
15:59
Polygenic Inheritance
Data 2fimages 2f0akhgujnqpcuh6kgrawu 190302 s4 afridi maham environmental influence vs genetic predisposition
09:37
Environmental Influence vs Genetic Predisposition
Data 2fimages 2fpioqag0trqez9vki8nqa 190302 s5 afridi maham clinical correlation
13:05
Clinical Correlation

Lecture´s Description

Multifactorial disorders have been elaborated in this sqadia.com medical video lecture. A comprehensive explanation is provided on the multifactorial inheritance, phenotype expression and empiric recurrence risk. Additionally, neural tube defects, diabetes and cleft palate has been shed light upon. Moreover, polygenic (oligogenic) inheritance along with heterozygotes and homozygotes, teratogens and fetal hydantoin syndrome.

Multifactorial Inheritance

Multifactorial inheritance has been highlighted in this section. Primarily, the features of such inheritance in addition to biological threshold has been elucidated. Moreover, phenotype expression and basic principles of inheritance (multifactorial traits) have also been elaborated thoroughly. Empiric recurrence risk, neural tube defects alongside two other conditions termed as cleft lip and cleft palate has been conversed about in-detail.

Example of Multifactorial Disorder

Example of multifactorial disorder has been explained in this section. Diabetes mellitus (DM) along with the genetic factors predisposing to type II DM has been delineated. Moreover, epigenetic and exogenous risk factors have been highlighted. Conclusively, environmental modifiers of DM have been comprehensively talked about.

Polygenic Inheritance

The prime focus of this section is on the polygenic (oligogenic) inheritance. Inheritance of height and accurate height estimation has been talked about quite comprehensively. In addition to this, short stature evaluation has been deliberated. Inheritance of intelligence has also been shed light on towards the end.

Environmental Influence vs Genetic Predisposition

Genetic susceptibility and factor V leiden have been explained broadly. Moreover, heterozygotes and homozygotes have been distinguished.                   Conclusively, preventive strategies have also been mentioned. It includes therapeutic and prophylactic heparin.

Clinical Correlation

Teratogens have been primarily talked about. This is followed by a discussion on the alcohol exposure and genetic susceptibility in fetal alcohol spectrum disorder. The educator has summed up by talking about fetal hydantoin syndrome (FHS).

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