Your browser is too old
We can't provide a great video experience on old browserUpdate now
Multifactorial disorders have been elaborated in this sqadia.com medical video lecture. A comprehensive explanation is provided on the multifactorial inheritance, phenotype expression and empiric recurrence risk. Additionally, neural tube defects, diabetes and cleft palate has been shed light upon. Moreover, polygenic (oligogenic) inheritance along with heterozygotes and homozygotes, teratogens and fetal hydantoin syndrome.
Multifactorial inheritance has been highlighted in this section. Primarily, the features of such inheritance in addition to biological threshold has been elucidated. Moreover, phenotype expression and basic principles of inheritance (multifactorial traits) have also been elaborated thoroughly. Empiric recurrence risk, neural tube defects alongside two other conditions termed as cleft lip and cleft palate has been conversed about in-detail.
Example of Multifactorial Disorder
Example of multifactorial disorder has been explained in this section. Diabetes mellitus (DM) along with the genetic factors predisposing to type II DM has been delineated. Moreover, epigenetic and exogenous risk factors have been highlighted. Conclusively, environmental modifiers of DM have been comprehensively talked about.
The prime focus of this section is on the polygenic (oligogenic) inheritance. Inheritance of height and accurate height estimation has been talked about quite comprehensively. In addition to this, short stature evaluation has been deliberated. Inheritance of intelligence has also been shed light on towards the end.
Environmental Influence vs Genetic Predisposition
Genetic susceptibility and factor V leiden have been explained broadly. Moreover, heterozygotes and homozygotes have been distinguished. Conclusively, preventive strategies have also been mentioned. It includes therapeutic and prophylactic heparin.
Teratogens have been primarily talked about. This is followed by a discussion on the alcohol exposure and genetic susceptibility in fetal alcohol spectrum disorder. The educator has summed up by talking about fetal hydantoin syndrome (FHS).