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The prime focal point of this sqadia.com medical video lecture is non-mendelian inheritance. This V learning lecture emphasizes upon the phenomena of mosaicism, X chromosome inactivation and uniparental disomy. Additionally, imprinting and its clinical implications have been elaborated. Furthermore, genetic heterogeneity, modifier genes along with antisense transcripts and hybrid dysgenesis has been highlighted. In the end, genetic anticipation has been explicated.
In the beginning, the term mosaicism has been elaborated. Following this, somatic mutations leading to mosaicism, X chromosome inactivation and mosaicism seen in cancers has been delineated. In addition to this, uniparental disomy and its proposed mechanism has been mentioned.
In the commencement of this section, the phenomenon of imprinting has been comprehensively explained. Furthermore, its probability in both mammals and humans have been explicated. Additionally, experimental exploration and monoallelic expression in imprinting has been shed light upon. Conclusively, scenarios of imprinting along with the requirement of imprinting has been highlighted.
Initially, genetic heterogeneity has been put forth. Moreover, digenic and multi-locus inheritance along with various modifiers genes have been conversed about in-detail. In the end, the educator has summed up by mentioning about the developmental buffering system.
Primarily, traditional process of transcription, opposite transcripts and certain transposable elements have been expansively talked about. In addition to this, retrotransposons, class II and class III transposons have been shed light upon. Conclusively, clinical implications of transposons and hybrid dysgenesis has been explained.
In the beginning, genetic anticipation has been comprehensively elaborated. Moreover, expanding trinucleotide repeats has been delineated. In the end, the section has been summed up by a mention of epigenetics.