Non-Mendelian inheritance diseases are the prime focus of this sqadia.com medical video lecture. This V learning lecture is a detailed elaboration of the somatic and gonadal mosaicism along with Marfan syndrome. Additionally, osteogenesis imperfecta, uniparental disomy, cystic fibrosis and imprinting has been brought to discussion. Furthermore, Prader-Willi and Angelman syndrome has also been explicated.
In the beginning, an overview of the somatic mosaicism has been put forth. Following this, Marfan syndrome and gonadal mosaicism has been brought under discussion. Additionally, osteogenesis imperfecta has been presented. In the end, a comparison between the germ-line and somatic mutations has been made.
The prime focus of this section is the uniparental disomy. Initially, this term has been described. Moreover, a condition termed as cystic fibrosis has been brought into consideration. In addition to this, certain CFTR mutations have been shed light upon.
Imprinting has firstly been described. Subsequently, Prader-Willi syndrome and Angelman syndrome has been explicated. Furthermore, genetic etiology of the latter has been highlighted. Inspite of this, certain disorders caused by anomalies in imprinting along with the opposite transcripts has been mentioned. Conclusively, interleukin-14 has been conversed about in-detail.