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Transport of Reabsorbed Substances
In this lecture ´´Renal Tubular Reabsorption and Secretion´´ is explained. Section one is about ´´Transport of Reabsorbed Substances´´. In the beginning of this section, tubular reabsorption is discussed. After that educator focuses on the active and passive mechanism of transport. The secondary active reabsorption and secretion is then explained in detail. Following that, transport maximum of reabsorbed substances is pursued. Subsequently, Passive water reabsorption of osmosis is elucidated. In the end, the reabsorption of chloride, urea and other solutes is demonstrated.
Section two is about “Tubular Reabsorption”. The educator begins the discussion by primarily focusing on the reabsorption and secretion along nephron. The concentration of solutes along proximal tubule is also demonstrated. After that, the secretion of organic acids and bases by proximal tubule is elucidated. Distal tubule is explained at the end of this section.
Late Distal Tubule and Medullary Conducting Duct
Section three is about ‘’Late Distal Tubule and Medullary Conducting Duct’’. In the beginning, late distal tubule and cortical collecting tubule is discussed. It is followed by the discussion about principle cells reabsorbing Na and secreting K. The educator then talks about intercalated cells which secrete/ reabsorb H ions, Bicarbonate and Potassium ions. After that, medullary collecting duct is demonstrated. A summary of tubular absorption is given at the end of the section.
Regulation of Tubular Reabsorption
Section four is about ‘’Regulation of Tubular Reabsorption’’. Initially, the regulation of tubular reabsorption is discussed. The educator then talks about the peritubular capillary and renal interstitial fluid physical forces. After that, regulation of peritubular capillary physical forces is pursued. Renal interstitial hydrostatic and colloid osmotic pressures are then focussed. Moreover, the effect of arterial pressure on urine output is highlighted. Hormonal control of tubular reabsorption is also covered in this section. The action of aldosterone, angiotensin II, atrial natriuretic peptide and parathyroid hormone secretion and reabsorption is then elucidated. Lastly, sympathetic nervous system activation is explained.
Quantification of Kidney Function
Section five is about ‘’Quantification of Kidney Function”. The educator firstly talks about clearance methods to quantify kidney functions. After that it is discussed how inulin clearance is used to estimate GFR. Furthermore, creatinine clearance and plasma creatinine concentration are explained in detail. Then PAH clearance is demonstrated by the educator, followed by the calculation of tubular reabsorption and secretion. In the end of this lecture, information about inulin clearance comparison with solutes is given.