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In this lecture ´´Thyroid and Antithyroid Drugs´´ are explained. Section one is about ´´Thyroid Hormone´´. Educator begins by introducing thyroid hormones. After that site of drug action illustrated. This is followed by explanation of chemistry. Then pharmacokinetics is discussed. Alongside mechanism of action is exhibited. Furthermore, effects of thyroid hormones are elucidated. Afterwards, drug effect and thyroid function is highlighted. Lastly, thyroid preparations are elaborated by the educator.
Section two is about ‘’Antithyroid Agents’’. Educator's prime focus is the elucidation of antithyroid agents. After that thioamides are discussed. This is followed by pharmacokinetics. Alongside its mechanism of action is illustrated. Then toxicity is explained. Next, anion inhibitors are focused. Following this iodides are discussed. Subsequently, pharmacodynamics, clinical use, and toxicity is elaborated in succession. Moreover, comprehensive information is conveyed about radioactive iodine. At last, adrenoceptor-blocking agents is explained.
Clinical Pharmacology: Hypothyroidism
Section three is about ‘’Clinical Pharmacology: Hypothyroidism’’. Educator's first theme of discussion is hypothyroidism. Then management of hypothyroidism is explained. Following this, special problems in management of hypothyroidism are highlighted. In the end of this section, drug-induced hypothyroidism is pursued.
Clinical Pharmacology: Hyperthyroidism
Section four is about ‘’Clinical Pharmacology: Hyperthyroidism’’. At first, hyperthyroidism is explained. After that grave’s diseases is discussed. Then information about management of graves’ diseases is delivered. Moving onward, adjuncts to antithyroid therapy are elaborated. In the end, educator emphasize neonatal graves’ disease.
Clinical Pharmacology of Special Problems
Section five is about ‘’Clinical Pharmacology of Special Problems’’. In the beginning, educator tells about toxic uninodular and multinodular goiter. After that subacute thyroiditis is discussed. Then thyroid storm comes under consideration. Alongside, information about dermopathy is given. Following this, thyrotoxicosis during pregnancy is elucidated. Furthermore, subclinical hyperthyroidism is explained. Nontoxic goiter is also considered in this section. Concluding this section, educator sheds light on Thyroid Neoplasms.