Thyroid Hormones

by Afridi, Maham

Biochemistry

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Ygyriwjvs0aqwzvt71cy 180623 s0 afridi maham thyroid hormones intro
04:19
Thyroid Hormones
Fpsjtzetlq0npox9bzix 180623 s1 afridi maham introduction
20:47
Introduction
Hpbeegqpmk1r9vilndeq 180623 s2 afridi maham role of iodine
27:26
Role of Iodine
Sfgntjoqwcu0dz05smx5 180623 s3 afridi maham mechanism of action
07:55
Mechanism of Action
M1h1bvvsvurbvvlzrhvq 180623 s4 afridi maham metabolic role
12:25
Metabolic Role
Zirawj7ntwilwpctrl39 180623 s5 afridi maham antithyroid drugs
06:03
Antithyroid Drugs

Lecture´s Description

Introduction
In this lecture ´´Thyroid Hormones´´ is explained. Section one is about ´´Introduction´´. Earlier in this section thyroid gland and its hormones is discussed. In the next slide hormones produced by follicular cells is explained. After that chemistry of thyroid hormones is the subject of discussion. Then biosynthesis of thyroid hormones is focused. Moving onward is thyroglobulin and chemistry of thyroglobulin. Next, educator tells that thyroid aciner cells have three functions. Lastly, proteins other than thyroglobulin and steps of thyroglobulin synthesis are discussed.


Role of Iodine
 Section two is about ‘’Role of Iodine’’. Iodine is the primary discussion here. In the next few slides steps of iodine incorporation in thyroid gland for synthesis of thyroid hormones are elucidated. After that extrathyroidal iodide uptake and iodide concentration is focused. Then oxidation of iodide is revealed. Next is the iodination of tyrosine. Moving onward coupling of iodotyrosines are pursued. Afterwards recycling of iodine in the gland is discussed. transport of iodine is pursued in the next slide. In the last slide educator reveals information about chemical hypertension.


Mechanism of Action
Section three is about ‘’Mechanism of Action’’. Earlier in this section mechanism of action of thyroid hormones is presented. Moreover, nuclear action, Na+ K+ ATPase Pump, and Translation of Proteins of thyroid hormones is discussed.


Metabolic Role
Section four is about ‘’Metabolic Role’’. In the very first slide metabolic role of thyroid hormones is discussed in which effects on protein metabolism comes under consideration. This is followed by the effects on carbohydrate metabolism. After that effects on lipid metabolism are pursued. Then calorigenic action is reported. In the last slide vitamins are discussed.


Antithyroid Drugs
Section five is about ‘’Antithyroid Drugs’’. Educator tells the mechanism of action of most of the drugs which inhibit thyroid function. Next, effect of iodine excess on thyroid gland is discussed. After that mechanism of action is reported. Finally, information about clinical importance is revealed. 

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