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Renin Angiotensinogen System
In this lecture ´´Vasoactive Peptides´´ are explained. Section one is about ´´Renin Angiotensinogen System´´. At first, educator explains vasoactive peptides. In the next slide, renin - angiotensin is discussed. After that information about renin is conveyed. Following this, angiotensinogen, ANG I and converting enzyme comes under consideration. Then angiotensinase is pursued. Likewise, RAAS is illustrated. Later on, educator talks about actions of angiotensin II. Moreover, angiotensin receptors and mechanism of action is elucidated. Inhibition of renin angiotensin system is also explained. In the end, prorenin receptors are elaborated.
Kallilkrein Kinin System
Section two is about ''Kallilkrein Kinin System''. Earlier in this section, biosynthesis of kinins is discussed. After that formation and metabolism of kinins is exhibited. Then discussion continues on physiologic and pathologic effects of kinins. This is followed by kinin receptors and mechanisms of action. Moving onward, drugs affecting the kallikrein kinin system are pursued. This include the elucidation of first-generation antagonists, second-generation antagonists, and third-generation antagonists.
Vasopressin and Natriuretic Peptides
Section three is about ''Vasopressin And Natriuretic Peptides''. Educator's first theme of discussion is vasopressin. This is followed by vasopressin receptors agonists. Then light is shed on therapeutic uses –vasopressin receptor agonists. Subsequently, vasopressin receptors antagonists are elaborated. Furthermore, natriuretic peptides (NPS) comes under consideration. Next, atrial natriuretic peptide (ANP) is focused. Brain natriuretic peptide (BNP) is discussed later on. Subsequently, urodilatin is pursued. Then pharmacodynamics and pharmacokinetics are elaborated. At last, clinical role of natriuretic peptides is explained.
Endothelins and Neurotensin
Section four is about ''Endothelins And Neurotensin''. Educator begins by explaining endothelins. Then elucidates its actions. Discussion continues on inhibitors of endothelins synthesis and action. Moreover, physiologic and pathologic roles of endothelin are reported. Afterwards, vasoactive intestinal peptides (VIP) are pursued. Then VIP-actions are focused. Next is the elaboration of substance P. This is followed by neurotensin (NT). Int the end, neurotensin effects are highlighted.
Section five is about ''Other Peptides''. Initially, calcitonin gene-related peptide is explained. After that adrenomedullin (AM) is elaborated. Then information about neuropeptide Y is delivered. Subsequently, urotensin is pursued. Lastly, UT receptors are elaborated.