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Want to learn about the acute infectious diarrhea? Here is what we have in stock for you. This sqadia.com medical video lecture, delivered by our medical specialist Dr Saima Mushtaq provides a comprehensive elaboration of acute infectious diarrhea. Pathogenic mechanisms including toxin production, cytotoxins and neurotoxins along with the host defenses like intestinal microbiota, immunity and genetic determinants have been conversed about. Additionally, epidemiology and diagnostic approach has been highlighted. Moreover, bacterial food poisoning, laboratory evaluation and treatment has been explained.
In the beginning of this section, an overview of acute diarrheal disease has been put forth. Subsequently, clinical manifestations have been conversed about in tabular form. Amongst the pathologic mechanisms, inoculum size, adherence and toxin production has been comprehensively elucidated. Additionally, enterotoxigenic strains of Escherichia coli, bacterial cytotoxins and neurotoxins have also been shed light upon. Conclusively, invasion by Shigella, Salmonella and Yersinia enterocolitica.
Various Host Defenses have been highlighted in this section. Primarily, intestinal microbiota and gastric acid has been delineated. Moreover, intestinal motility and immunity has also been conversed about. Towards the end, Dr Saima has explained about the genetic determinants and the phenomena of polymorphism.
Approach to the Patient
Taking patient history has its own significance in diagnosis of any infection. Similarly, in case of acute diarrheal disease, noting down history is important for the final consideration of empirical antimicrobial therapy. Furthermore, physical examination has also been highlighted. It generally includes the examination for the dehydration symptoms. In addition to this, diagnostic approach encompassing stool examination and test for fecal lactoferrin has also been discussed. The educator has summed up by elucidating about the post-diarrhea complications thoroughly.
A range of epidemiologic factors have been explained in this section. Majorly, travel history and location of the infection has been brought under consideration. Moving ahead, age and host immune status has been deliberated. Towards the end, bacterial food poisoning (by Bacillus cereus) and by Clostridium perfringens has been talked about.
Laboratory Evaluation and Treatment
Laboratory Evaluation has been firstly conversed about. this is followed by a discussion on the microbial identification along with the inflammatory disease evaluation. Moreover, evaluation of nosocomial diarrhea and evaluation of Escherichia coli has also been explained. Conclusively, treatment strategies like oral rehydration solution, IV solutions, antibiotics has been considered. Enterohemorrhagic Escherichia coli infection and prophylaxis has also been reported.