Your browser is too old
We can't provide a great video experience on old browserUpdate now
Keeping in mind the global need of medical knowledge, sqadia.com follows medical books that are accepted throughout the entire world, so that every medical student can get advantage of the medical lectures made by sqadia.com. The lecture benign and malignant diseases of prostate is also designed by following the instructions of the book of internal medicine i.e. ¨Harrison's Principles of Internal Medicine¨. This lecture explains prostate cancer and covers all its aspects ranging from overview and screening and diagnostic techniques available to staging and treatment options. In addition to this another medical condition entitled as benign prostatic hypertrophy has also been elaborately been elucidated.
For MBBS students, detailed explanation of prostate cancer is delivered under the lecture title benign and malignant diseases of prostate. The incident of benign and malignant changes occurring within the prostate gland increase with individual’s age. In case of benign proliferative disorders, symptoms can be weighed against the side effects and certain complications associated with intervention can also be observed. Alongside this, prostate malignancies can contribute to death. Prostate cancer can be hereditary and influences ethnic groups differently. It can be the polymorphic variants of AR, cytochrome P450 and SRD5A2. Isoflavonoid genistein and cruciferous vegetables consumption in addition to retinoids intake and inhibitors of cholesterol biosynthesis can be a few protective factors. This malady can be prevented via intake of statins, finasteride, dutasteride along with 5α-reductase inhibitors.
Screening and Diagnosis
Screening and diagnosis have also been deliberated comprehensively in the medical video lecture at the platform of sqadia.com for medical and MBBS students. Physical examination of the individual is a must. It is based upon the signs and symptoms the patient present with. It also demonstrates the changes in or elevated serum prostate surface antigen (PSA). This antigen is a marker of prostate cancer, and it contributes to liquefaction of seminal coagulum. One of the screening methods is based upon this antigen level detection. Levels found in blood are associated with risk and death occurs if levels lie in top quartile. In addition to this, prostate biopsy can also be taken from peripheral zone and can be visualized by transrectal ultrasound (TRUS) or MRI. More than 95% of this cancer are the adenocarcinomas. Moreover, the perineural invasion and extracapsular spread must also be examined.
Prostate Cancer Staging
At sqadia.com, according to the medical syllabus of internal medicine course, prostate cancer staging is also discussed under the chapter of benign and malignant disease of prostate. Staging of this medical condition is based upon TNM method. Based upon this, it has four grades ranging from T1-T4 in which T3 and T4 extend outside the gland. Digital rectal examination (DRE) alone is inaccurate in determination of disease extent, capsular invasion and disease spread to lymph nodes. Computerized tomography scan (CT) scan and MRI are carried out for diagnosis. In case of MRI, there are two types. One is T1-weighted MRI whereas, the other one is the T2-weighed MRI. Along with these, radionuclide bone scans are also carried out which evaluates the spread to the osseous sites and is quite a sensitive test.
Benign Prostatic Hypertrophy
The medical aspect of benign prostatic hypertrophy is also debated over in this medical lecture. This ailment is a pathologic process which is a contributor of lower urinary tract symptoms in males. It presents with certain obstructive (straining, voiding) and irritative (urgency, nocturia) symptoms. It can be treated via surgical resection. Besides this, uroflowmetry, pressure-flow studies and cystoscopy must also be carried out. In addition to surgery, other treatment options include alpha adrenergic receptor antagonists and 5α-reductase inhibitors along with Phosphodiesterase inhibitors (PDE) and anticholinergics. However, various surgical approaches include transurethral incision, stents and gland removal.